RNA-Mediated Regulation of HMGA1 Function
نویسندگان
چکیده
منابع مشابه
RNA-Mediated Regulation of HMGA1 Function
The high mobility group protein A1 (HMGA1) is a master regulator of chromatin structure mediating its major gene regulatory activity by direct interactions with A/T-rich DNA sequences located in the promoter and enhancer regions of a large variety of genes. HMGA1 DNA-binding through three AT-hook motifs results in an open chromatin structure and subsequently leads to changes in gene expression....
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2015
ISSN: 2218-273X
DOI: 10.3390/biom5020943